The 3-star Casa San Domenico Double Room A Valletta hotel provides proximity to St. George's Square, which is located only 500 metres away. Featuring Wi-Fi throughout the property, this Valletta guest house also has amenities such as a storage room.

The centre of Valletta can be reached within a 5-minute walk, and natural attractions like the compact harbourfront park "Lower Barrakka Gardens" are just a 5-minute stroll away. Standing merely 300 metres from Republic Street, the Casa San Domenico Double Room Valletta is merely 0.6 km from the Manoel Theatre. The hotel is situated not far from the Esplora Interactive Science Centre, while Valletta A1 bus station lies approximately a 5-minute drive away. For those travelling from afar, Malta International airport is 15 minutes' drive away.

The rooms at Casa San Domenico Double Room A hotel include climate control, as well as media facilities like a flat-screen TV with satellite channels. An iron with ironing board and an air conditioner are featured for guests' comfort. Offering a separate toilet and a shower, the bathrooms are fitted with a hair dryer and bath sheets.

Offering Mediterranean meals, Nenu The Artisan Baker is situated 150 m from the accommodation.